Speaker: Makoto Kaneko, Meijo University and Osaka University.
Date and venue: Thursday 30 November 2023, 14:15-15:15, JDB Seminar Room.
Title: New Innovative Idea on Bio Medical Research
Abstract: My talk begins with deformability of red blood cells under with and without nucleus. By utilizing an online high speed vision and a high speed actuator, we could succeed in fast and fine cell manipulation with the frequency of 100Hz and the resolution of 250 nanometers. As an application of cell manipulation, we show “Cell Stress Test” where a mechanical stress is continuously imparted to a cell until it eventually gets damages. We also show an interesting behavior of red blood cells where their recovery characteristics after three-minutes-loading in microchannel dramatically change. We discovered two-steps-recovery-process where 50% recover happens in the first step, and the remaining 45% in the second step. We also show “Cell Pinball” where this phenomenon can only be observed under red blood cell on limited condition. We tried to explain the principle why cell pinball behavior happens. We also discuss how human can keep their life in space center under zero gravity. We show our hypothesis where our brain activity correlates with the deformability of red blood cell. Finally, we show a new “Cell Exercise” where a cell under periodic pressure results in twice more contact areas between cell and bottom than those under atmospheric pressure during one hour.
Short bio: Dr. Makoto Kaneko (M’88-SM’03-F’06 for IEEE) is a professor of the Department of Mechanical Engineering, Graduate School of Engineering, Osaka University. He received Ph.D. at the University of Tokyo in 1981. His current research interests include dynamic active sensing, He has received more than 40 awards, including the Humboldt Research Award in 1997, the IEEE ICRA Best Manipulation Paper Award in 2000, the IEEE ISATP Outstanding Paper Award in 2001, the IEEE RAS King-Sun Fu Memorial Best Transactions Paper Award in 2003, the IEEE ICIA Best Conference Paper Award in 2005, the IEEE MHS Best Paper Award in 2012 and 2014, IEEE Int. Conf. on Cyborg and Bionic Systems, the Best Paper Award in 2017. He also received the Honorary Doctor from Darmstadt University of Technology, Germany in 2013.
We strongly encourage you to attend the seminar in person.
You can also connect via Zoom: https://newnham.zoom.us/j/92544958528?pwd=YS9PcGRnbXBOcStBdStNb3E0SHN1UT09
Meeting ID: 925 4495 8528
Passcode: 203369
